Bremelanotide
Also known as PT-141, Vyleesi
An injection that increases sexual desire. Approved in the US for women before menopause with low libido (Vyleesi).
Quick facts
- Status
- Approved medicine in the US
- Evidence
- Approved in the US (phase 3 trials)
- Taken as
- Injection under the skin before sexual activity
- Common sizes
- 10 mg
- Category
- Sexual function
How it works
It acts on melanocortin receptors in the brain that are involved in sexual desire.
What it’s used for
- Low sexual desire in pre-menopausal women (approved in the US)
- Libido and erections in men (not approved)
What the research shows
Phase 3 trials showed a modest increase in desire.
Side effects & risks
- Nausea — very common
- Flushing and headache
- A short rise in blood pressure
- Darker skin patches with repeated use
Is it legal?
Approved in the US (FDA). Not approved in the EU or UK.
Storage & safe handling
- Only use as prescribed and supervised by a doctor.
- Store exactly as described in the patient leaflet.
- Use a new sterile needle every time and dispose of it in a sharps container.
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Sources: FDA prescribing information for Vyleesi.
Last updated 12 October 2026. Information — not medical advice. PepTimer does not replace a doctor. Many peptides are not approved medicines in the EU, UK or US. Talk to a qualified healthcare provider before starting, changing or stopping any treatment.
Last updated 12 October 2026. Information — not medical advice. PepTimer does not replace a doctor. Many peptides are not approved medicines in the EU, UK or US. Talk to a qualified healthcare provider before starting, changing or stopping any treatment.