Cagrilintide
Also known as NN9838
A long-acting version of amylin, a hormone that helps you feel full. It's being developed together with semaglutide.
Quick facts
- Status
- Investigational — not approved yet
- Evidence
- Investigational (phase 2–3 trials, mostly as CagriSema)
- Taken as
- Injection under the skin once a week (in trials)
- Common sizes
- 5 mg, 10 mg
- Category
- Amylin analogue · weight (investigational)
How it works
Amylin is released with insulin after meals and tells your brain you've eaten enough. It works on a different route from GLP-1 drugs, so the two can add up.
What people use it for
Weight loss (in clinical trials, mostly combined with semaglutide as CagriSema)
What the research shows
- Studied in phase 2 and 3 trials, mainly as part of CagriSema.
- On its own it gives moderate weight loss; combined with semaglutide the effect is larger.
- Not approved yet.
Side effects & risks
- Nausea, vomiting, diarrhoea and constipation, mainly when starting
- Products sold online are not the trial drug
Is it legal?
Investigational — not approved in the EU or US as of October 2026. Novo Nordisk submitted the combination CagriSema to the FDA in December 2025; check for the outcome of the review.
Storage & safe handling
- Mix with bacteriostatic water: let it run slowly down the inside of the vial and swirl gently — never shake.
- Store the mixed vial in the fridge and follow the use-by period on the label.
- Wipe the vial top with alcohol and use a new sterile needle and syringe every time.
- Rotate injection sites so the same spot is not used again and again.
- Put used needles in a sharps container, not the household bin.
- Get medical help for redness that spreads, fever, swelling or trouble breathing.
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Sources: Novo Nordisk REDEFINE trial programme; FDA submission announcement for CagriSema (December 2025).
Last updated 12 October 2026. Information — not medical advice. PepTimer does not replace a doctor. Many peptides are not approved medicines in the EU, UK or US. Talk to a qualified healthcare provider before starting, changing or stopping any treatment.
Last updated 12 October 2026. Information — not medical advice. PepTimer does not replace a doctor. Many peptides are not approved medicines in the EU, UK or US. Talk to a qualified healthcare provider before starting, changing or stopping any treatment.