FOXO4-DRI
Also known as Proxofim
An experimental peptide that clears out old, worn-out ("zombie") cells in mice.
Quick facts
- Status
- Not an approved medicine
- Evidence
- Preclinical (mouse studies)
- Taken as
- Injection (experimental)
- Common sizes
- 10 mg
- Category
- Senolytic peptide (experimental)
How it works
It makes worn-out cells that refuse to die finally self-destruct, leaving healthy cells alone.
What people use it for
Anti-ageing (experimental)
What the research shows
- A 2017 mouse study showed improved fitness, fur and kidney function in old mice.
- No human trials.
Side effects & risks
- Unknown in humans
- Very expensive and often impure when sold online
Is it legal?
Not an approved medicine in the EU, UK or US. In most countries it is illegal to sell it for use in people. Products labelled "research use only" are not checked for quality or purity.
Storage & safe handling
- Mix with bacteriostatic water: let it run slowly down the inside of the vial and swirl gently — never shake.
- Store the mixed vial in the fridge and follow the use-by period on the label.
- Wipe the vial top with alcohol and use a new sterile needle and syringe every time.
- Rotate injection sites so the same spot is not used again and again.
- Put used needles in a sharps container, not the household bin.
- Get medical help for redness that spreads, fever, swelling or trouble breathing.
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Sources: Baar MP et al., "Targeted apoptosis of senescent cells restores tissue homeostasis in response to chemotoxicity and aging", Cell 2017.
Last updated 12 October 2026. Information — not medical advice. PepTimer does not replace a doctor. Many peptides are not approved medicines in the EU, UK or US. Talk to a qualified healthcare provider before starting, changing or stopping any treatment.
Last updated 12 October 2026. Information — not medical advice. PepTimer does not replace a doctor. Many peptides are not approved medicines in the EU, UK or US. Talk to a qualified healthcare provider before starting, changing or stopping any treatment.