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Gonadorelin

Also known as GnRH, LHRH, Factrel

A lab-made copy of GnRH, the brain hormone that controls the sex hormones.

Quick facts

Status
Not an approved medicine
Evidence
Established as a diagnostic; limited data for off-label uses
Taken as
Injection
Common sizes
2 mg
Category
Hormone · reproductive axis

How it works

Short bursts tell the pituitary to release LH and FSH. Constant exposure can do the opposite and shut them down.

What people use it for

  • Testing the hormone system (diagnostic)
  • Keeping testosterone production during steroid use (not approved)

What the research shows

  • Established as a hospital test.
  • Little evidence for the uses it's sold for online.

Side effects & risks

  • Headache, nausea and flushing
  • Allergic reactions (rare)
  • Banned in sport for men

Is it legal?

Has been authorised in some countries as a diagnostic agent and for specific fertility uses; the US product (Factrel) is no longer marketed. Not an approved medicine for the uses it is promoted for online (e.g. maintaining testosterone during steroid use). Prohibited in sport for males (WADA).

Storage & safe handling

  • Mix with bacteriostatic water: let it run slowly down the inside of the vial and swirl gently — never shake.
  • Store the mixed vial in the fridge and follow the use-by period on the label.
  • Wipe the vial top with alcohol and use a new sterile needle and syringe every time.
  • Rotate injection sites so the same spot is not used again and again.
  • Put used needles in a sharps container, not the household bin.
  • Get medical help for redness that spreads, fever, swelling or trouble breathing.
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Sources: FDA records for Factrel (gonadorelin); WADA Prohibited List.
Last updated 12 October 2026. Information — not medical advice. PepTimer does not replace a doctor. Many peptides are not approved medicines in the EU, UK or US. Talk to a qualified healthcare provider before starting, changing or stopping any treatment.