KPV
Also known as Lys-Pro-Val, α-MSH fragment
A tiny peptide (three amino acids) that calms inflammation. Mostly studied for gut inflammation.
Quick facts
- Status
- Not an approved medicine
- Evidence
- Preclinical (cell and animal studies)
- Taken as
- Injection or capsules
- Common sizes
- 10 mg
- Category
- Anti-inflammatory peptide (experimental)
How it works
It switches down inflammation signals inside cells, especially in the gut lining.
What people use it for
- Gut inflammation (e.g. colitis)
- Skin inflammation
What the research shows
- Promising results in mice with colitis.
- No human trials.
Side effects & risks
- Unknown in humans
- Product quality is not checked
Is it legal?
Not an approved medicine in the EU, UK or US. In most countries it is illegal to sell it for use in people. Products labelled "research use only" are not checked for quality or purity.
Storage & safe handling
- Mix with bacteriostatic water: let it run slowly down the inside of the vial and swirl gently — never shake.
- Store the mixed vial in the fridge and follow the use-by period on the label.
- Wipe the vial top with alcohol and use a new sterile needle and syringe every time.
- Rotate injection sites so the same spot is not used again and again.
- Put used needles in a sharps container, not the household bin.
- Get medical help for redness that spreads, fever, swelling or trouble breathing.
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Sources: Dalmasso G et al., "PepT1-mediated tripeptide KPV uptake reduces intestinal inflammation", Gastroenterology 2008.
Last updated 12 October 2026. Information — not medical advice. PepTimer does not replace a doctor. Many peptides are not approved medicines in the EU, UK or US. Talk to a qualified healthcare provider before starting, changing or stopping any treatment.
Last updated 12 October 2026. Information — not medical advice. PepTimer does not replace a doctor. Many peptides are not approved medicines in the EU, UK or US. Talk to a qualified healthcare provider before starting, changing or stopping any treatment.