Semax
Also known as ACTH(4-7)-Pro-Gly-Pro
A nasal-spray peptide used in Russia for stroke recovery and focus.
Quick facts
- Status
- Not an approved medicine
- Evidence
- Limited (mainly Russian studies)
- Taken as
- Nasal spray or injection
- Common sizes
- 5 mg, 10 mg
- Category
- Nootropic peptide
How it works
It's based on a fragment of the stress hormone ACTH and may raise BDNF, a protein that supports brain cells.
What people use it for
- Stroke recovery (approved in Russia)
- Focus and memory (claimed)
What the research shows
- Mostly Russian studies.
- Few independent trials.
Side effects & risks
- Nose irritation
- Limited independent safety data
Is it legal?
Registered as a medicine in Russia and some neighbouring countries (e.g. for stroke recovery). Not approved in the EU, UK or US.
Storage & safe handling
- Store as directed on the product, usually in the fridge once opened.
- Don't share the spray bottle with anyone.
- Stop and seek advice if you get nosebleeds or persistent irritation.
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Sources: Russian clinical and preclinical studies of Semax (Institute of Molecular Genetics, Moscow).
Last updated 12 October 2026. Information — not medical advice. PepTimer does not replace a doctor. Many peptides are not approved medicines in the EU, UK or US. Talk to a qualified healthcare provider before starting, changing or stopping any treatment.
Last updated 12 October 2026. Information — not medical advice. PepTimer does not replace a doctor. Many peptides are not approved medicines in the EU, UK or US. Talk to a qualified healthcare provider before starting, changing or stopping any treatment.